EPA ratings · 2020 · Mercedes-Benz · E-Class
2020 Mercedes-Benz E-Class Fuel Economy
EPA rates the 2020 Mercedes-Benz E-Class's 13 trims from 18 to 26 MPG combined, AMG E63 S 4matic Plus to E350. The table below prices every trim per mile at a fuel price and mileage you can change.
EPA ratings by trim
| Trim | Engine | Transmission | Drive | City | Hwy | Combined |
|---|---|---|---|---|---|---|
| AMG E53 4matic Plus · Premium | 3 L, 6 cyl, Hybrid | Automatic 9-spd | 4-Wheel Drive | 21 | 28 | 24 MPG |
| AMG E53 4matic Plus Convertible · Premium | 3 L, 6 cyl, Hybrid | Automatic 9-spd | 4-Wheel Drive | 20 | 26 | 23 MPG |
| AMG E53 4matic Plus Coupe · Premium | 3 L, 6 cyl, Hybrid | Automatic 9-spd | 4-Wheel Drive | 21 | 28 | 23 MPG |
| AMG E63 S 4matic Plus · Premium | 4 L, 8 cyl | Automatic 9-spd | 4-Wheel Drive | 15 | 23 | 18 MPG |
| AMG E63 S 4matic Plus (wagon) · Premium | 4 L, 8 cyl | Automatic 9-spd | 4-Wheel Drive | 16 | 23 | 19 MPG |
| E350 · Premium | 2 L, 4 cyl | Automatic 9-spd | Rear-Wheel Drive | 23 | 32 | 26 MPG |
| E350 4matic · Premium | 2 L, 4 cyl | Automatic 9-spd | 4-Wheel Drive | 22 | 30 | 25 MPG |
| E450 4matic · Premium | 3 L, 6 cyl | Automatic 9-spd | 4-Wheel Drive | 20 | 28 | 23 MPG |
| E450 4matic (station wagon) · Premium | 3 L, 6 cyl | Automatic 9-spd | 4-Wheel Drive | 19 | 26 | 22 MPG |
| E450 4matic Convertible · Premium | 3 L, 6 cyl | Automatic 9-spd | 4-Wheel Drive | 19 | 26 | 22 MPG |
| E450 4matic Coupe · Premium | 3 L, 6 cyl | Automatic 9-spd | 4-Wheel Drive | 19 | 26 | 22 MPG |
| E450 Convertible · Premium | 3 L, 6 cyl | Automatic 9-spd | Rear-Wheel Drive | 20 | 27 | 23 MPG |
| E450 Coupe · Premium | 3 L, 6 cyl | Automatic 9-spd | Rear-Wheel Drive | 20 | 28 | 23 MPG |
City and highway are EPA's adjusted label figures; combined is the 55/45 blend printed on the window sticker. For electric and plug-in trims the MPG columns are MPGe, and the kWh per 100 miles is the figure a charging cost actually turns on; EPA measures it at the wall, so charging losses are already in it. Unrounded combined figures, where EPA publishes them: AMG E53 4matic Plus 24.01; AMG E53 4matic Plus Convertible 22.5517; AMG E53 4matic Plus Coupe 23.3607; AMG E63 S 4matic Plus 17.5069; AMG E63 S 4matic Plus (wagon) 18.5852; E350 26.2664; E350 4matic 24.9303; E450 4matic 22.7114; E450 4matic (station wagon) 21.8116; E450 4matic Convertible 21.8041; E450 4matic Coupe 21.739; E450 Convertible 22.6853; E450 Coupe 22.9182.
What the rating costs per mile
The rating divided by a price, times your miles. It starts at EIA's current U.S. averages and EPA's 15,000 miles so the right-hand column is comparable; type your own pump price, home rate and mileage over them.
| Trim | Runs on | Rated | Per mile | Per year | EPA's figure |
|---|---|---|---|---|---|
| AMG E53 4matic Plus | Premium Gasoline | 24 MPG | 17.8¢ | $2,678 | $3,400 |
| AMG E53 4matic Plus Convertible | Premium Gasoline | 23 MPG | 18.6¢ | $2,794 | $3,550 |
| AMG E53 4matic Plus Coupe | Premium Gasoline | 23 MPG | 18.6¢ | $2,794 | $3,550 |
| AMG E63 S 4matic Plus | Premium Gasoline | 18 MPG | 23.8¢ | $3,570 | $4,550 |
| AMG E63 S 4matic Plus (wagon) | Premium Gasoline | 19 MPG | 22.5¢ | $3,382 | $4,350 |
| E350 | Premium Gasoline | 26 MPG | 16.5¢ | $2,472 | $3,150 |
| E350 4matic | Premium Gasoline | 25 MPG | 17.1¢ | $2,570 | $3,300 |
| E450 4matic | Premium Gasoline | 23 MPG | 18.6¢ | $2,794 | $3,550 |
| E450 4matic (station wagon) | Premium Gasoline | 22 MPG | 19.5¢ | $2,921 | $3,750 |
| E450 4matic Convertible | Premium Gasoline | 22 MPG | 19.5¢ | $2,921 | $3,750 |
| E450 4matic Coupe | Premium Gasoline | 22 MPG | 19.5¢ | $2,921 | $3,750 |
| E450 Convertible | Premium Gasoline | 23 MPG | 18.6¢ | $2,794 | $3,550 |
| E450 Coupe | Premium Gasoline | 23 MPG | 18.6¢ | $2,794 | $3,550 |
Per mile = price ÷ rated MPG (gasoline) or price per kWh × kWh per 100 miles ÷ 100 (electricity). Per year = per mile × miles. EPA's figure is its own annual fuel cost at 15,000 miles, 55% city, and the national price in force when the file was built; it will differ from the middle columns whenever the price here differs. A plug-in hybrid is shown once on each fuel; its real cost sits between them, by how much of its driving is on the battery.
Fuel only — before depreciation, insurance, maintenance or tires, which the True Cost per Mile Calculator adds. Most drivers land below the rating; the True MPG Calculator measures your own from two fill-ups.
EPA's own figures, and why they differ
The “EPA's figure” column is EPA's annual fuel cost from the same file: 15,000 miles, 55% city, and the national fuel price fueleconomy.gov was using on the day the file was built (2026-09-29). fueleconomy.gov recomputes its page every week at the current price, so its number and the file's drift apart between file dates; the middle columns here use a price you can see and change, which is the only honest way to compare two cars. EPA also prints a five-year “you save/spend” against the average new vehicle (spends $3,750 for the E350); it rests on the same assumptions and is not repeated here as a result.
Every figure on this page is a rating, not a measurement of any particular car. The site never calls a rating wrong; it shows what your own price and miles do to it. See the model on fueleconomy.gov.
Other model years of the Mercedes-Benz E-Class: 2027, 2026, 2025, 2024, 2023, 2022, 2021, 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, 2011, 2010, 2009, 2008, 2007, 2006, 2005, 2004, 2003, 2002, 2001, 2000, 1999, 1998, 1997, 1996, 1995, 1994.
Related tools
Price the same miles on gasoline and on electricity, using your fuel price, your utility rate, and each car's rated efficiency.
Open tool →True MPG CalculatorYour car's real fuel economy from two odometer readings and a fill-up — and how far it falls from its EPA rating.
Open tool →Commute Cost CalculatorWhat getting to work costs per day, per month, and per year — energy only, or all-in at the IRS standard mileage rate.
Open tool →Gas Prices by Region and StateThis week's average price of regular gasoline for the U.S., every state and ten cities, from EIA's weekly survey — a dated figure to start from, never one assumed for you.
Open tool →Electricity Prices by StateThe average residential price of electricity in every state, by month, from EIA's utility filings — and what each rate does to a mile in an electric car.
Open tool →Informational only — published averages for scale and comparison, not a quote for any pump, utility or vehicle. Your own price is the one that counts, and every calculator on this site takes it as an input.
Ratings: U.S. EPA and U.S. DOE, fueleconomy.gov vehicles.csv dated 2026-09-29 (EPA record ids 41735, 41704, 41703, 42240, 42252, 41962, 42005, 41809, 41817, 41795, 41793, 41794, 41792). Prices: EIA, U.S. regular gasoline week of October 19, 2026; U.S. residential electricity August 2026. Snapshots refreshed monthly.