EPA ratings · 2020 · Mercedes-Benz · S-Class
2020 Mercedes-Benz S-Class Fuel Economy
EPA rates the 2020 Mercedes-Benz S-Class's 13 trims from 16 to 23 MPG combined, AMG S65 to S560e. Electric and plug-in trims show MPGe and kWh per 100 miles. The table below prices every trim per mile at a fuel price and mileage you can change.
EPA ratings by trim
| Trim | Engine | Transmission | Drive | City | Hwy | Combined | kWh/100 mi | Electric range |
|---|---|---|---|---|---|---|---|---|
| AMG S63 4matic Plus · Premium | 4 L, 8 cyl | Automatic 9-spd | 4-Wheel Drive | 17 | 26 | 20 MPG | — | — |
| AMG S63 4matic Plus Convertible · Premium | 4 L, 8 cyl | Automatic 9-spd | 4-Wheel Drive | 15 | 24 | 18 MPG | — | — |
| AMG S63 4matic Plus Coupe · Premium | 4 L, 8 cyl | Automatic 9-spd | 4-Wheel Drive | 17 | 27 | 20 MPG | — | — |
| AMG S65 · Premium | 6 L, 12 cyl | Automatic 7-spd | Rear-Wheel Drive | 13 | 22 | 16 MPG | — | — |
| Maybach S650 · Premium | 6 L, 12 cyl | Automatic 7-spd | Rear-Wheel Drive | 13 | 21 | 16 MPG | — | — |
| S450 · Premium | 3 L, 6 cyl | Automatic 9-spd | Rear-Wheel Drive | 19 | 28 | 22 MPG | — | — |
| S450 4matic · Premium | 3 L, 6 cyl | Automatic 9-spd | 4-Wheel Drive | 18 | 28 | 22 MPG | — | — |
| S560 · Premium | 4 L, 8 cyl | Automatic 9-spd | Rear-Wheel Drive | 17 | 27 | 21 MPG | — | — |
| S560 4matic · Premium | 4 L, 8 cyl | Automatic 9-spd | 4-Wheel Drive | 17 | 27 | 21 MPG | — | — |
| S560 4matic Coupe · Premium | 4 L, 8 cyl | Automatic 9-spd | 4-Wheel Drive | 17 | 26 | 20 MPG | — | — |
| S560 4matic Maybach · Premium | 4 L, 8 cyl | Automatic 9-spd | 4-Wheel Drive | 16 | 25 | 19 MPG | — | — |
| S560 Convertible · Premium | 4 L, 8 cyl | Automatic 9-spd | Rear-Wheel Drive | 17 | 26 | 20 MPG | — | — |
| S560e · Premium and Electricity | 3 L, 6 cyl, Plug-in Hybrid | Automatic 9-spd | Rear-Wheel Drive | 21 | 26 | 23 MPG | 53.0 | 19 mi |
City and highway are EPA's adjusted label figures; combined is the 55/45 blend printed on the window sticker. For electric and plug-in trims the MPG columns are MPGe, and the kWh per 100 miles is the figure a charging cost actually turns on; EPA measures it at the wall, so charging losses are already in it. Unrounded combined figures, where EPA publishes them: AMG S63 4matic Plus 20.0251; AMG S63 4matic Plus Convertible 17.9865; AMG S63 4matic Plus Coupe 20.2762; AMG S65 15.5264; Maybach S650 15.5665; S450 21.973; S450 4matic 21.7132; S560 20.5095; S560 4matic 20.7551; S560 4matic Coupe 20.1091; S560 4matic Maybach 19.4129; S560 Convertible 20.1785; S560e 22.8263.
What the rating costs per mile
The rating divided by a price, times your miles. It starts at EIA's current U.S. averages and EPA's 15,000 miles so the right-hand column is comparable; type your own pump price, home rate and mileage over them.
| Trim | Runs on | Rated | Per mile | Per year | EPA's figure |
|---|---|---|---|---|---|
| AMG S63 4matic Plus | Premium Gasoline | 20 MPG | 21.4¢ | $3,213 | $4,100 |
| AMG S63 4matic Plus Convertible | Premium Gasoline | 18 MPG | 23.8¢ | $3,570 | $4,550 |
| AMG S63 4matic Plus Coupe | Premium Gasoline | 20 MPG | 21.4¢ | $3,213 | $4,100 |
| AMG S65 | Premium Gasoline | 16 MPG | 26.8¢ | $4,016 | $5,150 |
| Maybach S650 | Premium Gasoline | 16 MPG | 26.8¢ | $4,016 | $5,150 |
| S450 | Premium Gasoline | 22 MPG | 19.5¢ | $2,921 | $3,750 |
| S450 4matic | Premium Gasoline | 22 MPG | 19.5¢ | $2,921 | $3,750 |
| S560 | Premium Gasoline | 21 MPG | 20.4¢ | $3,060 | $3,900 |
| S560 4matic | Premium Gasoline | 21 MPG | 20.4¢ | $3,060 | $3,900 |
| S560 4matic Coupe | Premium Gasoline | 20 MPG | 21.4¢ | $3,213 | $4,100 |
| S560 4matic Maybach | Premium Gasoline | 19 MPG | 22.5¢ | $3,382 | $4,350 |
| S560 Convertible | Premium Gasoline | 20 MPG | 21.4¢ | $3,213 | $4,100 |
| S560e — on gasoline | Premium Gasoline | 23 MPG | 18.6¢ | $2,794 | $3,550 |
| S560e — on electricity | Electricity | 53 kWh/100 mi | 9.6¢ | $1,444 | — |
Per mile = price ÷ rated MPG (gasoline) or price per kWh × kWh per 100 miles ÷ 100 (electricity). Per year = per mile × miles. EPA's figure is its own annual fuel cost at 15,000 miles, 55% city, and the national price in force when the file was built; it will differ from the middle columns whenever the price here differs. A plug-in hybrid is shown once on each fuel; its real cost sits between them, by how much of its driving is on the battery.
Fuel only — before depreciation, insurance, maintenance or tires, which the True Cost per Mile Calculator adds. Most drivers land below the rating; the True MPG Calculator measures your own from two fill-ups. The EV vs. Gas Cost Calculator sets the electric trim against a gasoline one over a year.
EPA's own figures, and why they differ
The “EPA's figure” column is EPA's annual fuel cost from the same file: 15,000 miles, 55% city, and the national fuel price fueleconomy.gov was using on the day the file was built (2026-09-29). fueleconomy.gov recomputes its page every week at the current price, so its number and the file's drift apart between file dates; the middle columns here use a price you can see and change, which is the only honest way to compare two cars. EPA also prints a five-year “you save/spend” against the average new vehicle; it rests on the same assumptions and is not repeated here as a result.
Every figure on this page is a rating, not a measurement of any particular car. The site never calls a rating wrong; it shows what your own price and miles do to it. See the model on fueleconomy.gov.
Other model years of the Mercedes-Benz S-Class: 2027, 2026, 2025, 2024, 2023, 2022, 2021, 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, 2011, 2010, 2009, 2008, 2007, 2006, 2005, 2004, 2003, 2002, 2001, 2000, 1999, 1998, 1997, 1996, 1995, 1994.
Related tools
Price the same miles on gasoline and on electricity, using your fuel price, your utility rate, and each car's rated efficiency.
Open tool →True MPG CalculatorYour car's real fuel economy from two odometer readings and a fill-up — and how far it falls from its EPA rating.
Open tool →Commute Cost CalculatorWhat getting to work costs per day, per month, and per year — energy only, or all-in at the IRS standard mileage rate.
Open tool →Gas Prices by Region and StateThis week's average price of regular gasoline for the U.S., every state and ten cities, from EIA's weekly survey — a dated figure to start from, never one assumed for you.
Open tool →Electricity Prices by StateThe average residential price of electricity in every state, by month, from EIA's utility filings — and what each rate does to a mile in an electric car.
Open tool →Informational only — published averages for scale and comparison, not a quote for any pump, utility or vehicle. Your own price is the one that counts, and every calculator on this site takes it as an input.
Ratings: U.S. EPA and U.S. DOE, fueleconomy.gov vehicles.csv dated 2026-09-29 (EPA record ids 42198, 42194, 42196, 42393, 42392, 41815, 41816, 42197, 42199, 42195, 42200, 42193, 42525). Prices: EIA, U.S. regular gasoline week of October 19, 2026; U.S. residential electricity August 2026. Snapshots refreshed monthly.